KomivesLab

Specializing in Biophysics Research

E3 Ligases

Lumpkin RJ, Ahmad AS, Blake R, Condon CJ, Komives EA. (2021) The Mechanism of NEDD8 Activation of CUL5 Ubiquitin E3 Ligase. Mol Cell Proteomics. 20:100019

Lumpkin RJ, Baker RW, Leschziner AE, Komives EA. (2020) Structure and dynamics of the ASB9 CUL-RING E3 Ligase.  Nat Commun. 11(1):2866

Schiffer JM, Malmstrom RD, Parnell J, Ramirez-Sarmiento C, Reyes J, Amaro RE, Komives EA (2016) Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer. Structure 2;24(8):1248-56). PMC4972691

Balasubramaniam D, Schiffer J, Parnell J, Mir SP, Amaro RE, Komives EA. (2015) How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase. Biochemistry 54(8):1673-80.

Lumpkin RJ, Baker RW, LEschziner AE, Komives EA. (2020) Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nat Commun. 11(1): 2866.

Lumpkin RJ, Ahmad AS, Blake R, Condon CJ, Komives EA (2020) The mechanism of NEDD8 activation of CUL5 Ubiquitin E3 ligases (2021) Mol Cell Proteomics 20:100019.