{"id":61,"date":"2016-08-03T19:50:18","date_gmt":"2016-08-03T19:50:18","guid":{"rendered":"http:\/\/localhost:8888\/wordpress\/?page_id=61"},"modified":"2024-04-30T03:56:40","modified_gmt":"2024-04-30T03:56:40","slug":"welcome-to-the-komives-lab-at-ucsd","status":"publish","type":"page","link":"https:\/\/komiveslab.ucsd.edu\/","title":{"rendered":"Welcome to the Komives Lab at UCSD"},"content":{"rendered":"<h2>\r\n\t<div class=\"slideshow_container slideshow_container_style-light\" style=\"height: 500px; \" data-slideshow-id=\"313\" data-style-name=\"style-light\" data-style-version=\"2.3.1\" >\r\n\r\n\t\t\t\t\t<div class=\"slideshow_loading_icon\"><\/div>\r\n\t\t\r\n\t\t<div class=\"slideshow_content\" style=\"display: none;\">\r\n\r\n\t\t\t<div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i0.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/KomivesLab.jpg?fit=1280%2C853&amp;ssl=1\" alt=\"KomivesLab\" width=\"1280\" height=\"853\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/GroupPhoto.jpg?fit=850%2C619&amp;ssl=1\" alt=\"groupphoto\" width=\"850\" height=\"619\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i2.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/NFkB.jpg?fit=1524%2C844&amp;ssl=1\" alt=\"Print\" width=\"1524\" height=\"844\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i0.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/SUMOfigureCOLORSimple_640x-1.png?fit=640%2C535&amp;ssl=1\" alt=\"SUMO Analysis\" width=\"640\" height=\"535\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i2.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/thrombin_500px.jpg?fit=500%2C647&amp;ssl=1\" alt=\"thrombin_500px\" width=\"500\" height=\"647\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/HDX500px.jpg?fit=500%2C649&amp;ssl=1\" alt=\"hdx500px\" width=\"500\" height=\"649\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t<div class=\"slideshow_title\">hdx500px<\/div>\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/SPR_strip_500px.jpg?fit=745%2C500&amp;ssl=1\" alt=\"spr_strip_500px\" width=\"745\" height=\"500\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t<div class=\"slideshow_title\">spr_strip_500px<\/div>\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div><div class=\"slideshow_view\">\r\n\t\t\t\t<div class=\"slideshow_slide slideshow_slide_image\">\r\n\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/2016\/09\/smFRET2_350px.jpg?fit=988%2C350&amp;ssl=1\" alt=\"smfret2_350px\" width=\"988\" height=\"350\" \/>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"slideshow_description_box slideshow_transparent\">\r\n\t\t\t\t\t\t<div class=\"slideshow_title\">smfret2_350px<\/div>\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<div style=\"clear: both;\"><\/div><\/div>\r\n\t\t<\/div>\r\n\r\n\t\t<div class=\"slideshow_controlPanel slideshow_transparent\" style=\"display: none;\"><ul><li class=\"slideshow_togglePlay\" data-play-text=\"Play\" data-pause-text=\"Pause\"><\/li><\/ul><\/div>\r\n\r\n\t\t<div class=\"slideshow_button slideshow_previous slideshow_transparent\" role=\"button\" data-previous-text=\"Previous\" style=\"display: none;\"><\/div>\r\n\t\t<div class=\"slideshow_button slideshow_next slideshow_transparent\" role=\"button\" data-next-text=\"Next\" style=\"display: none;\"><\/div>\r\n\r\n\t\t<div class=\"slideshow_pagination\" style=\"display: none;\" data-go-to-text=\"Go to slide\"><div class=\"slideshow_pagination_center\"><\/div><\/div>\r\n\r\n\t\t<!-- WordPress Slideshow Version 2.3.1 -->\r\n\r\n\t\t\t<\/div>\r\n\r\n<\/h2>\n\n\n<p class=\"has-text-align-center\"><strong>Current Lab<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/komiveslab.ucsd.edu\/wordpress\/wp-content\/uploads\/image.png?resize=640%2C478\" alt=\"\" class=\"wp-image-815\" width=\"640\" height=\"478\" srcset=\"https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/image.png?w=648&amp;ssl=1 648w, https:\/\/i1.wp.com\/komiveslab.ucsd.edu\/wp-content\/uploads\/image.png?resize=300%2C224&amp;ssl=1 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" data-recalc-dims=\"1\" \/><figcaption class=\"wp-element-caption\">                                                                                                                        <\/figcaption><\/figure><\/div>\n\n\n<p> Work in the Komives Lab is focused on understanding the parameters that govern protein-protein interactions mediated by non-globular proteins. Four main systems are currently under study. We were the first lab to do amide H\/D exchange to understand what happens to the solvent accessibility of the protein-protein interface during protein-protein interactions. The systems currently under study include the thrombin-thrombomodulin interaction, the NFkB signaling system, the Cullin 5 E3 ligases and the urokinase-uPAR interaction. The lab consists of one postdoctoral fellow, six graduate students and three undergraduate students. Our lab oversees the the Biomolecular and Proteomics Mass Spectrometry at UCSD which includes a Waters Synapt G2Si HDX Mass spectrometer and a LUMOS. The lab is also a member of the NMR User Group at UCSD. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Current Lab Work in the Komives Lab is focused on understanding the parameters that govern protein-protein interactions mediated by non-globular proteins. Four main systems are currently under study. We were the first lab to do amide H\/D exchange to understand what happens to the solvent accessibility of the protein-protein interface during protein-protein interactions. The systems currently under study include the<\/p>\n<div class=\"clearfix\"><\/div>\n<div class=\"pull-left padding-top-25\"><a href=\"https:\/\/komiveslab.ucsd.edu\/\" class=\"btn btn-theme\">Continue reading<span class=\"screen-reader-text\"> &#8220;Welcome to the Komives Lab at UCSD&#8221;<\/span> <i class=\"fa fa-fw fa-long-arrow-right\"><\/i> <\/a>  <\/div>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"spay_email":"","footnotes":""},"class_list":["post-61","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/61","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=61"}],"version-history":[{"count":6,"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/61\/revisions"}],"predecessor-version":[{"id":819,"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/61\/revisions\/819"}],"wp:attachment":[{"href":"https:\/\/komiveslab.ucsd.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=61"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}